-
2024
Ribosome demand links transcriptional bursts to protein expression
noise
Pal S., Ray U., Dhar R†
eLife (2024)
-
2024
Exaptation and de novo mutations transcend cryptic variations as drivers
of adaptation in yeast
Routh S., Lindsay R., Gudelj I., Dhar R†
bioRxiv (2024)
-
2024
Living in a noisy world: origins of gene expression noise and its role in
cellular decision-making
Pal S., Dhar R†
FEBS Letters (2024, in press)
-
2024
Increased heterogeneity in expression of genes associated with cancer
progression and drug resistance
Bose A., Datta S., Mandal R., Ray U., Dhar R†
Translational Oncology 41:101879 (2024)
-
2022
Transcription factor binding process is the primary driver of noise in
gene expression
Parab L*, Pal S*, Dhar R†
PLoS Genetics 18:e1010535 (2022)
-
2022
EpICC: A Bayesian neural network model with uncertainty correction for a
more accurate classification of cancer
Joshi P., Dhar R†
Scientific Reports 12:14628 (2022)
-
2022
Designer bacterial cell factories for improved production of commercially
valuable non-ribosomal peptides
Mitra S., Dhar R†, Sen R†
Biotechnol Adv. 60:108023 (2022)
-
2022
A large-scale computational screen identifies strong potential inhibitors
for disrupting SARS-CoV-2 S-protein and human ACE2 interaction
Singh A., Dhar R†
J Biomol Struct Dyn. 40:9004-9017 (2022)
-
2021
A two-step PCR assembly for construction of gene variants across large
mutational distances
Routh S*, Acharyya A*, Dhar R†
Biology Methods and Protocols 6:bpab007 (2021)
-
2020
Role of mitochondria in generation of phenotypic heterogeneity in
yeast
Dhar R†
Journal of the Indian Institute of Science 100:497-514 (2020)
-
2019
Changes in gene expression predictably shift and switch genetic
interactions
Li X., Lalic J., Baeza-Centurion P., Dhar R., Lehner B.
Nature Communications 10:3886 (2019)
-
2019
Single cell functional genomics reveals the importance of mitochondria in
cell-to-cell phenotypic variation
Dhar R†, Missarova A. M., Lehner B*, Carey L. B*
eLife 8:e38904 (2019)
-
2016
Liquid Phase Separation as a Mechanism of Overexpression-induced Dosage
Sensitivity
Bolognesi B, Gotor NL, Dhar R, Cirillo D, Baldrighi M, Tartaglia GG,
Lehner B.
Cell Reports 16: 222–231 (2016)
-
2015
Slow growing cells within isogenic populations have increased RNA
polymerase error rates and DNA damage
van Dijk D., Dhar R., Missarova A. M., Espinar L., Blevins W., Lehner
B., Carey L. B.
Nature Communications 6:7972 (2015)
-
2014
Increased gene dosage plays a predominant role in the initial stages of
evolution of duplicate TEM-1 beta lactamase genes
Dhar R, Bergmiller T, Wagner A.
Evolution 68:1775-1791 (2014)
-
2013
Yeast adapts to a changing stressful environment by evolving
cross-protection and anticipatory gene regulation
Dhar R., Sägesser R., Weikert C., Wagner A.
Molecular Biology and Evolution 30:573-588 (2013)
-
2011
Adaptation of Saccharomyces cerevisiae to saline stress through laboratory
evolution
Dhar R., Sägesser R., Weikert C., Yuan J., Wagner A.
Journal of Evolutionary Biology 24:1135-1153 (2011)
-
2009
Analyzing the catalytic mechanism of protein tyrosine phosphatase PtpB
from Staphylococcus aureus through site-directed mutagenesis
Mukherjee S*, Dhar R*, Das AK.
International Journal of Biological Macromolecules 45:463-469 (2009)
(* equal contribution)
-
2009
Interface of apoptotic protein complexes has distinct properties
Mitra P, Dhar R, Pal D.
In Silico Biology 9:365-378 (2009)
